The Pros And Cons Of Vaccines

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INTRODUCTION Vaccines are used widely in the world. With the discovery of various vaccines mortality rate caused by various infectious organisms have reduced. Their use has been considered one of the safe and effective measures to control various infectious diseases. Plants offer enormous potential as production platforms for vaccines and therapeutic proteins. Vaccines derived from plants present an alternative to conventional vaccines by facilitating safe and effective oral delivery through intake of edible plant tissue. Numerous infectious diseases enter the body through mucosal surfaces such as the gut, and as a result, vaccines expressed in the form of edible plant tissues offer a selective advantage. Plant tissues protect the antigen as it passes…show more content…
There is no need of facilities like sterilization as required in traditional vaccines. • They are more accepted, as they don’t require the process of injecting unlike traditional vaccines. • The risk of contamination is reduced • Plant derived vaccines could be the source for new vaccines combining numerous antigens that are called second-generation vaccines. • Edible vaccines give better protection to individuals as compared to traditional vaccines since there is no possibility of proteins to reform into infectious organism. • They are easy to produce in bulk. Limitations of Edible vaccines • Easy to access but still associated with major problems like: 1. Possibility of development of immunotolerance to the vaccine protein or peptide. 2. Constancy of dosage form is different in every plant, fruit and every generation. 3. Stability of vaccine in fruit is unknown. 4. Some food cannot be consumed raw and needs cooking which weakens the protein content in it. 5. Selection of the best plant is difficult. 6. Evaluating dosage requirements is difficult. 7. Glycosylation pattern of plants and humans is different which could affect the functions of
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