Pglo Lab Report

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Transformation in human biology is the process of transferring genetic information from one organism to another. In the Transformation Lab completed in class, bacteria was used to replicate the transformation process in combination with pGLO plasmid and Transformation Solution. pGLO is a plasmid that contains ori bla, ara, and GCF. To understand the process of transformation using a pGLO plasmid, one must be acquainted with the functions of the aforementioned properties. Within the pGLO, an ori is where DNA replication begins. bla is an enzyme that codes for beta-lactamase. This enzyme presents bacteria from being killed. AraC is the gene coding for the arabinose C protein. GFP is a jellyfish gene that codes for the production of Green Fluorescent Protein. To conduct this lab, we took two microtubes filled with…show more content…
We added plasmid DNA to the +pGLO solution and not the -pGLO solution. After that, we incubated both solutions and then added LB broth to them and incubated them once more again. We then labeled 4 petri dishes: two solutions without pGLO (-pGLO), and the other two containing pGLO (+pGLO). On one +pGLO petri dish we added ampicillin, while on the other we added ampicillin and arabinose. On one –pGLO petri dish, we added ampicillin, and on the other one we added nothing. These four petri dishes were then incubated overnight. The next day when they were observed underneath a UV light, LB/amp +pGLO had produced colonies but there was no color, meanwhile the LB/amp/ara also had produced colonies but with color. The LB –pGLO only created slime in the dish, meanwhile the LB/amp produced no colonies of bacteria. On

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