Green Tea Research Paper

1250 Words5 Pages
3. Epigallocatechin-3-gallate Green tea (Camellia sinensis) is one of the most popular beverages throughout the world and therefore being explored extensively for its health benefits. History of green tea goes back to 3rd century, during the years Chinese gradually refined the technique for better tasting, and became part of their society. In early 1900’s green tea moved out by the traders and introduced to the rest of the world. In India its commercial production was started by East India Company in attempt to break the Chinese monopoly (Colleen Taylor Sen (2004). Food Culture in India. Greenwood Publishing Group. p.26–.ISBN 978-0-313-32487-1). Camellia sinensis is evergreen shrub grown mainly in tropical and subtropical climates. The composition of its leaves depends on various factors including climate, area, temperature and type of tea plant. In general green tea contain caffeine (1–5%),…show more content…
Moreover, cytosolic COMT mediated methylation is more for EGCG compare to other catechin like EGC in rat liver (Zhu et al., 2000, Zhu et al., 2001). At low concentration of EGCG (3µM) 4″-O-methyl-EGCG is predominant metabolite (Lu et al., 2003b) Another interesting observation is that catechin inhibits the COMT activity while D-ring and B-ring play important roles in it. EGCG metabolites, 4″-O-methyl-EGCG and 4′,4″-di-O-methyl-EGCG, inhibit COMT noncompetitively by binding to sites other than the catechol binding site (Lu et al., 2003b) Because other transferases like SAM-dependent methyltransferases and DNA methyltransferases share common catalytic domain structure with the COMT, so it is quite possible that EGCG or its metabolites might also inhibit them (Cheng, 1995). This prediction was strongly supported the fact that EGCG is strong inhibitors of human liver COMT-mediated O-methylation of catechol estrogens (Nagai et al.,

More about Green Tea Research Paper

Open Document