Scarred skin in comparison to normal skin will be with no hair follicles and sebaceous glands, thus the penetration is more in injured or abraded skin 9. Physiochemical Factors 10 1. Partition coefficient Drug should have some lipid solubility for absorption but at the same time, it should be hydrophilic to diffuse through skin. Thus drug should have optimum partition coefficient. 2. Molecular weight (<400 Dalton) It is generally believed that larger the molecular weight slower is the drug permeation
2. Experimental 2.1 Materials and reagents Pyrrole (Spectrochem Pvt. Ltd, Mumbai) was double distilled and stored in refrigerator before use. Ferric Chloride (anhydrous) and trisodium citrate were procured from S. D. Fine Chem. Ltd., Mumbai. Silver Nitrate was purchased from Research Lab Fine Chem. Industries, Mumbai. These chemicals were of AR grade and were used as received. All solutions of reacting materials were prepared in distilled water. 2.2 Synthesis of Polypyrrole Polypyrrole (PPy) was
Among the different RSM experimental designs, the Full face-cantered central composite design (CCD) was employed. CCD is one of the excellent tools to establish RSM model. It is a flexible and efficient model of RSM that was provided the maximum amount of data on the effects of parameters with a minimum number of experiments (PCR, RSM 10). First, the appropriate variables and the range of selected variables were determined by preliminary
silver particle covers the active sites of titania which prevents light absorption as well as the absorption of organic substrate from contacting the titania surface thereby reducing the efficiency of TiO2 photocatalyst. The results showed that titania containing 1% silver exhibited high photocatalytic activity due to the following reasons; (i) its lower band gap value (3.07 eV) causes effective light absorption and (ii) separation of electron-hole pair recombination by silver metal.
Introduction The word inflammation comes from a Latin word “Inflammare” which means “to set on fire” [1]. Inflammation is a protective response done by our body to protect itself from injury, foreign microorganisms as well as initiate healing and repair process. However, inflammation can also be potentially harmful to our body because of the chemicals involve in inflammation process which are capable to destroy and injure normal tissues. The components of inflammatory process are white blood cells
blood [1] and is used as a model protein for most of the biophysical, biochemical and physicochemical studies [2]. These proteins exhibit the interesting properties of binding to a variety of hydrophobic ligands such as fatty acids, lysolecithin, bilirubin, warfarin, tryptophan, steroids, several dyes etc. The drugs (more than 90%) like analgesics, anesthetics, tranquilizers,
ultra-small objects with its dimensions measure in nanometers (nm) and typically this nanomaterials properties dimensions that has less than 100nm in size. This nanomaterials has their own unique properties because of their large surface area for reaction. The nanomaterials used in this study is graphene oxide. Graphene oxide nanomaterials can be used for many applications such as air purification, water treatment, anti-bacterial, and self-cleaning because of their effective photo-catalytic activity
warfare agents including autoinjectors, for rapid administration and faster absorption of drugs. The autoinjectors are safe and available for life saving drugs like atropine sulphate and pralidoxime chloride (nerve agent poisoning), epinephrine (anaphylaxis), diazepam (seizures) and sumatriptan (migraine). For bio-threat agents doxycycline
Synthesis of Polythiophene by Using MgO and Different Stabilizers for Separating Cd (II) from Aqueous Solution Abstract - The goal of this work is to study the sorption characteristic of Polythiophene nanocomposites for eliminating Cd(II) from aqueous solution. The products were characterized in the terms of morphology, particle size, and chemical structure by using scanning electron microscope (SEM), X-ray diffraction, and FTIR. FTIR spectrum analysis confirms that nanocomposite is formed in the
Hernandez-Luna C, Valdez-Anaya B, Maldonado-Vega M, Lopez-Miranda A. Author information Abstract A 3 years study was conducted to determine the evolution of blood lead concentrations (PbB) and free erythrocyte protoporphyrins (FEP) as indicators of absorption and biochemical damage in children (7-12 years old) living within one kilometer of a metallurgic factory that processes lead in Torre?n, Coahuila, M?xico. In addition, neuromuscular conduction velocity, motor coordination and IQ where determined