Advantages And Disadvantages Of Detergent

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INTRODUCTION Detergents are designed for cleaning purposes. They are often used for assisting the removal of dirt or other materials from contaminated surfaces. The active chemical ingredients of detergents are termed as surfactants or surface-active agents (Scott et al., 2000; Yahaya et al., 2011). Detergent formulations consist of surface-active agents, surfactants. Thus, they are called as amphiphilic substances because one part of the detergent is hydrophilic and the other part is hydrophobic. In common usage, typical anionic "detergent" refers to alkylbenzenesulfonates. The alkylbenzene portion of these anions is lipophilic and the sulfonate is hydrophilic (Prats et al., 1997). Two varieties of detergents have been popular: branched…show more content…
The alterations in haematological profiles due to a surfactant, sodium dodecyl sulfate, in rabbits (Wadaan and Mubarak, 2009) and an anionic detergent in Sprague Dawley rats (Dehelean et al., 2004) had been previously reported. Haematological profiles are known to provide important information about the internal environment of mammals. The environmental factors reported to pose a variety of adverse effects on the haematological profiles of most organisms. In the current study, there was a decrease in hemoglobin levels of the mice in TR4 and TR5. It is possible that the constituents in detergent might have interacted with hemoglobin synthesis. Decrease in hemoglobin synthesis could be associated with liver damage, or iron absorption from small intestine. Similarly, total neutrophils and eosinophils were increased only within the two highest dose detergent treatment groups. This could be a result of immune and allergic response to the toxic components of the detergent. The increased neutrophil production indicates a stimulation of the immune system which protects the mice against infection that might have been caused by chemical and also secondary infections. This may be directly proportional to the severity of the causative stress condition, may be attributed to an increase in neutrophil…show more content…
Ayandiran et al. (2009) previously reported histopathological changes in muscle tissues of detergent exposed catfish. Ogundiran et al (2010) also reported a multi-organ damages due to detergent exposure in catfish. Similarly, heart, lung and liver damage was apparent in mice treated with detergent solutions (Yahaya et al., 2011). Biochemical markers are often used as basis for the assessment of toxicity of an organ. Rise in ALP activities indicates non-specific tissue irritation and usually suggests a toxic effect on the liver with bile duct alterations. AST is found in the heart, kidney, brain, liver, and skeletal muscle. Consequently, an increase in AST activity may be the result of liver, heart or muscle damage. Therefore, higher blood concentrations of ALP and AST in treated mice suggest liver damage, as was paralleled with decreased plasma protein

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