Type 1 Diabetes: A Case Study

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United Kingdom (UK): The UK guideline for screening and includes: 1. Random plasma glucose ≥ 11 mmol/litre with polyuria, polydipsia, weight loss, excessive tiredness. [2004, amended 2015] 2. Refer children and young people with suspected type 1 diabetes on the same day to a multidisciplinary paediatric diabetes team and confirm diagnosis using plasma glucose criteria as per WHO 2006. [2004, amended 2015]. Assume type 1 diabetes unless strong indications of T2DM, monogenic or mitochondrial diabetes (see recommendations [new 2015]) 3. Consider T2DM in children and young people with suspected diabetes with: strong family history; obesity; Black/Asian family origin; requiring no insulin or less than 0.5 units/kg body weight/day after the partial remission phase; or show evidence of insulin resistance i.e. acanthosis nigricans [2004, amended 2015] 4.…show more content…
Consider types of diabetes other than types 1 or 2 (such as other insulin resistance syndromes, or monogenic or mitochondrial diabetes) in children and young people who have any of the following features: diabetes in the first year of life; no ketonaemia during episodes of hyperglycaemia; optic atrophy; retinitis pigmentosa; deafness; or another systemic illness or syndrome. [2004, amended 2015] 5. Do not measure C peptide and/or diabetes specific autoantibody titres at initial presentation but consider if there is difficulty later to distinguish between type 1 diabetes and other types. [new

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