parameters chosen for the optimization were Dissolution efficiency at 10 min and In-vitro dispersion time. Data analysis was carried out by multiple linear regression analysis. Differential Scanning Calorimetry (DSC) and Attenuated total reflection (ATR) reports shown that there is no interaction between drug and excipients. Results: Four optimized formulations F1 to F4 are selected from the numerical optimization technique. The prepared formulations were evaluated for different pre-compression and post-compression