ABSTRACT
Background The success of chemotherapy lies in the continuous search for new drugs to counter the challenge posed by resistant microbes. Moringa oleifera has been traditionally used in Indian folklore medicine for the treatment of various microbial infections. Objective To investigate antifungal activity and explore the phytochemistry of methanolic and ethyl acetate leaf extracts of M. oleifera. Methods Disc diffusion and broth dilution methods were used for antifungal activity and standard qualitative chemical tests for the identification of phytoconstituents. Results Both the plant extracts showed antifungal activity against Rizopus stolonifer and Microsporum gypsum. Ethyl acetate extract was more active against M. gypsum, while R. stolonifer was more sensitive to methanolic…show more content… Wagner H and Bladt S. Plant Drug Analysis: A Thin Layer Chromatography Atla Second edition. Springer-Verlag Berlin Heidelberg, New York, Tokyo. 1994; 384. Harborne JB. Phytochemical Methods. Springer (India) Pvt. Ltd., New Delhi. 2005; 17.
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