What Role Does Leptin Play In The Regulation Of Muscle
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Leptin play an important role in the regulation of appetite. It is often called the "satiety or hunger hormone". It reduces food intake and increases energy expenditure by acting on the brain via the hypothalamus. Leptin is secreted in adipose tissue (fat cell), therefore we can suppose that the more fat someone have, the more leptin will be produced and the higher his/her metabolic rate. However if this is correct, why overweight people are always hungry? They do have enough fat, thus enough leptin secreted in order to feel full...
One of the explanation found is that when leptin reaches its threshold, it communicates with the brain, in consequences the individual feels full.
When leptin goes beyond its threshold, the brain does not receive