The Similarities And Differences Between Sense And Missense Stereotypes
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Both sense and missense mutations are forms of point mutations, which occur by change or substitution in the DNA code but differ in the effect that they incur [1, 2]. First of all, to understand these two mutations it should be known that to code for 20 amino acids, there are 61 codons; many of these codons are degenerate, which means that different codons code for the same amino acids. For example, if CAA is changed to CAT, it will still code for valine. Thus it is possible that a base is substituted in a DNA to produce a codon that still codes for the same amino acid having no effect on the protein to be formed from the altered gene. Such a point mutation is called sense, silent, or synonymous mutation. On the contrary, when the base change