Universally, typhoid fever affects roughly 21.7 million people annually, causing 600,000 deaths. Although it is rare in developed countries, there are many cases that are because of returning from Africa and Southeast Asia, which it is endemic in. In contrast, some people are not completely cured, and they become asymptomatic carriers such as Mary Mallon, which means that the human body maintains an infectious disease and displays no symptoms. An incubation of typhoid varies from three to sixteen days. Urine, feces, and unclean drinks and foods convey this disease. Additionally, typhoid is an infection caused by Salmonella Typhi, which relates to the bacteria that cause salmonella food poisoning. It has a long history, several symptoms that are similar to other disease, and varies treatments(SPECIFY WHEN I FIND THE SPI. TREAT).…show more content… She was born in 1869 in Ireland. Then she immigrated to the United States in 1884 after she was infected by salmonella typhi. Charles Henry Warren, a wealthy New York banker, had engaged her as a cook in 1906. Then people in that house were infected by typhoid, in addition to approximately 3,000 New Yorkers. With no antibiotics treatment until 1984, it was necessary to isolate Mary Mallon. Thus, she was persuaded by doctors and police to give samples that were positive. Therefore, she was forcedly sent to the hospital in North Brother Island, which is located in New York City's East River, until she died in