Research Paper On Atherosclerosis

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Atherosclerosis is a disease that involves the luminal narrowing of the arteries through the formation of plaques within specific sites of the arterial walls (Bentzon et al., 2014). The plaques have internal regions of necrosis, which is a form of cell death, where they have been heavily invaded by macrophages. These plaques are vulnerable to rupturing, releasing thrombogenic substances into the bloodstream, which could lead to a myocardial infarction (Fok, 2011). The word atherosclerosis was originally derived from Greek “athero” which meant wax in relation to the necrotic core area located at the bottom of an atherosclerotic plaque, and “sclerosis” which meant hardening, in relation to the fibrous cap on top of the plaque’s luminal surface

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