Diagnosis of Lady Macbeth Macbeth is a tragedy written by William Shakespeare. In this epic tragedy, the two main characters are Macbeth and Lady Macbeth. She shortly starts planning the death of King Duncan and convinces Macbeth to kill him. Lady Macbeth manipulates Macbeth and makes him feel like he isn’t a man unless he kills Duncan. The actions of Lady Macbeth make it clear that she is suffering from paranoid schizophrenia. Paranoid schizophrenia is the most common type of schizophrenia in most parts