Dr. H. H. Holmes Dr. Henry Howard Holmes was considered a well groomed, intelligent, up incoming business man. He was admired by many of the locals in Chicago because he was becoming very successful very fast, already acquiring a pharmacy of his own. What the locals did not know was that Holmes was far from what he had seemed, acquiring most of his fortune through fraud, forgery, and even murder. Holmes tended to prey on people mostly women and women that were rich and had very few family ties.