appreciation of antioxidants for prevention and treatment of diseases, and maintenance of human health. Antioxidants are compounds that inhibit or delay the oxidation of other molecules by inhibiting the initiation or propagation of oxidizing chain reactions. There are two basic categories of antioxidants, namely, synthetic and natural. In general, synthetic antioxidants are compounds with phenolic structures of various degree of alkyl substitution, whereas natural antioxidants can be phenolic compounds
E1cB mechanism stands for Elimination Unimolecular conjugate Base. In elimination, the mechanism is an elimination reaction and it will eliminate to substituents. Unimolecular refers to the rate-determining step of this reaction only involves one molecular entity. The second way to synthesize curcumin was through the process of microwave-assisted reaction. Nonetheless, both processes had the same goal and that was to synthesize curcumin and both ways has achieved that