Pharmacology Lab Report

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According to the Pharmacology textbook about 80% of drugs are taking orally. The first phase of the drug action is the Pharmaceutic phase or dissolution. Where a drug that is in a solid form tablet must disintegrate into smaller particle before it can dissolve into a liquid. And medication that are administered parenterally by SUBQ, IM or IV routes does not go trough pharmaceutic phase because it is a liquid. Tablets are not 100% drug because they have to use other substances called excipients in order for the drug to get certain size shape and also to go to the process of dissolution. Older adults and little children have less gastric acidity therefore drug absorption are slower especially drugs absorb via the stomach. Enteric coated drugs or capsules should not be crushed in order not to alter the effect of the drug. Drugs that can irritate the stomach should be given with foods or fluids in order to dilute the drug concentration. Pharmacokinetic Phase: The process of how the drug moves throughout the body. It goes to four processes Absorption, Distribution, Metabolism, or biotransformation and ecretion, or elimination.…show more content…
And it is also influence by blood flow. It is important to take into consideration the protein level in each patient because that can affect the effectiveness of the drug action. Some drugs are more bound to protein then the others. Those that are at 89% are considered to be highly protein-bound drugs; While 61 to 89% are moderately bound to protein. The remaining drugs that are not bound to protein are called free drugs, they are active and cause drug toxicity. Patients with liver or kidney diseases, and malnourished need to be monitored closely because their albumin level may be low therefore they are at risk for drug
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