Nutrition And Metabolism Essay

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JC5 ARTICLE 1 REPORT DRAFT: FORM Student Name Farina Syed Research Type Nutrition and Metabolism Reference (Harvard Format) References: Yang, H, Kwon, D, Kim, M, Kang, S, Moon, N, Daily, J, and Park, S 2015, ‘Red peppers with moderate and severe pungency prevent the memory deficit and hepatic insulin resistance in diabetic rats with Alzheimer’s disease’, Nutrition and Metabolism 12, 9, pp. 1-12, Academic Search Complete, EBSCOhost, viewed 13 September 2015 SUMMARY: IN YOUR OWN 50-100 WORDS and complete sentences, describe What This Article Was About And The Main Findings. Use PAST TENSE and PASSIVE STYLE (no pronouns). Cite Reference with (1). Multiple articles suggested that red peppers lower the level of insulin for type 2 diabetic…show more content…
(3) Compared to the incidence of dementia, the incidence of Alzheimer disease is expected to increase by about 3 to 1 fold from 2010 to 2050. Current evidence suggests that in the brain, possibly marginal insulin resistance and hyperglycemia are the key metabolic dysfunctions causative to Alzheimer’s disease. Abnormalities in insulin levels, particularly insulin growth factor-1 (IGF-1), reveal that the hippocampus in the brain has been implicated in Alzheimer disease. Furthermore, dementia was a gradually established disorder that intersects worldwide with the prevalence of type 2 diabetes mellitus (DM2). However, It was look more to imagine that the incidence of DM2 rises the possibility of developing dementia, due to its harmful effect on the cerebral vasculature and the related hormonal and metabolic change.(2)However, dementia caused by β-amyloid accretion disrupts peripheral glucose homeostasis, and red pepper recovers glucose homeostasis. The data demonstrate that long-term oral ingestion of different red peppers repair cognitive dysfunction and glucose homeostasis in type 2 diabetic rats with β-amyloid-induced dementia. Additionally, red peppers of different color and pungencies influence glucose homeostasis effect an different kind of metabolic rats.…show more content…
The B-amyloid (25-35)AD and (35-25) Non-AD is dissolve by sterling solution and filled into the cannula protected in joint CA1 subregions of the hippocampus using an osmotic pump (Alzet Osmotic Pump Company, Cupertino, CA, USA) at the rate of 3.6 n mol/day on behalf of 14 days. The β-amyloid (35–25) had the opposite sequence of β-amyloid (25–35) and did not gather in the brain and it was not noticed by immunohistochemistry (normal-control). Px rats imbued with β-amyloid (25–35) were arbitrarily given to four dissimilar groups of 20 animals, which were separately fed Western diets with high dietary fat to encourage insulin confrontation and accompanied with also 1% dextrin (AD-CON) or 1% of moreover mild pungency red pepper extract (AD-LP), moderate pungency red pepper extract (AD-MP), and severe pungency red pepper (AD-SP). Px rats infused with β-amyloid (35–25) had Western diets covering 1% dextrin as a normal control (Non-AD-CON). The rats were expended water and conforming diets grounded on AIN-93 diet for 47 days.
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