Medical/Physiological aspects of Myasthenia Gravis Myasthenia gravis (MG) is a neuromuscular autoimmune disease in which nerve impulses traveling to the muscles are disrupted at the neuromuscular junction due to an autoimmune reaction that destroys or blocks Acetylcholine (ACh) receptors necessary for initiating voluntary muscle contractions of the body (NINDS, 2010). Typically, nerve impulses are released from the nerve into the neuromuscular junction where they then bind to a corresponding receptor located on the
1. INTRODUCTION : 1.1 Alzheimer’s disease (AD) : Frequency of the Neurodegenerative diseases keeps on increasing with increasing age. Neurodegenerative disease is a common term for various conditions because of chronic breakdown and deterioration of neurons(Houghton and Howes, 2005). Alzheimer’s disease is one of the prevalent neurodegenerative disease. Alzheimer’s disease was named after its discoverer Alois Alzheimer in 1906 who is a Bavarian neuropsychiatrist(1-1) Ageing is the main risk factor
Chemical synapses are junctions in which cells of the nervous system signal one another and to non-neuronal cells such as glands or muscles. There are different chemical synapses such as neuromuscular junction, which includes motor neurons and muscle cells. The chemical synapses that compute our perception and thought, are the ones that form interconnected neural circuits
The modern era of science is full of genetic wonders. Genetic engineering is a huge step in the expansion of human health and welfare. This new technique is already used in foods, but there is great potential for it in gene therapy and other medical procedures. The process of food engineering alleviates the need for insecticides while increasing crop yield. Gene therapy removes diseased genes and inserts the new and improved. Some medicines to benefit the human condition can only be created through
4. DRUG AND EXCIPIENT PROFILE 4.1 DRUG PROFILE (Oxybutynin chloride)60,61,62,63 A. Molecular Weight: 393.96 B. Chemical Formula: C22H31NO3 • HCl C. Melting point: 124 – 129°C. D. Description: White crystalline, practically odourless powder. E. Solubility: Freely soluble in water and in alcohol; very soluble in methanol and in chloroform; soluble in acetone; slightly soluble in ether; very slightly soluble in hexane. F. IUPAC Name: Benzeneacetic acid, α-cyclohexyl-α-hydroxy,-4-(diethylamino)-2-butynyl
(PbB) and free erythrocyte protoporphyrins (FEP) as indicators of absorption and biochemical damage in children (7-12 years old) living within one kilometer of a metallurgic factory that processes lead in Torre?n, Coahuila, M?xico. In addition, neuromuscular conduction velocity, motor coordination and IQ where determined as indicators of physiological damage. During this period of time the children showed increased lead
According to this sliding filament theory a nerve impulse came along the axon of the nerve cell and it reaches the junction of the neuromuscular. There are bulbs like structures found in the edges of the axons called as pre synaptic terminal. Synaptic vessels are found in pre synaptic terminal. These vessels go ahead and attached to the pre synaptic membrane and release the acetylcholine
being activated is what determines how strong the muscle contraction is. If multiple motor units are being fired continuously then the muscle is being constantly contracted. To begin a muscle contraction, an action potential is created at the neuromuscular junction and moved along the sarcolemma. When it reaches the T tubule, the action potential is sent on the T tubule membrane into the interior of the muscle of
slightly forward, squats down to a pre-determined height and immediately jumps up from that position. The counter movement jump is more of a short duration preloading of the musculotendinous junction followed by an immediate contraction. In other words, the counter movement jump is more of a proprioceptive neuromuscular facilitation or plyometric type of movement versus the squat
Background: Acquired Brain Injury is a condition caused by trauma or infection and is often linked to poor health standards such as obesity and drug use. Side effects of acquired brain injury often result in poor balance and coordination, upper limb weakness or numbness, cognitive processing difficulties and slurred speech. Virtual reality therapy is an emerging method of rehabilitation in occupational therapy services. Current research evaluates the efficacy of virtual reality in rehabilitating