Nephrosis Case Studies

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1. How would a pneumococcal infection lead to glomerulonephritis? How can glomerulonephritis result in nephrosis? Although there is not a clear relationship between glomerulonephritis and streptococcal infections; it is believed the streptococcus produce antigen-antibody complexes that travel to the walls of the glomerulus and cause inflammation (Copstead-Kirkhorn & Banasik, 2014, p. 586). With time there are ongoing fibrotic changes, and the tubulointerstitial damage will usually cause a reduction in kidney function. Nephrons will start atrophying and the kidneys will become small and not able to function until the patient finally gets to the final stage of renal disease and dialysis or transplantation are required (Copstead-Kirkhorn & Banasik, 2014, p. 586). 2.…show more content…
Use JH’s laboratory values to determine if he is still experiencing nephrosis or if his condition is progressing to renal failure. JH clinical findings indicate the he is still suffering from nephrosis. High serum levels of phosphates, low levels of protein in the urine, and low levels of serum sodium are usually seen in nephrosis (Copstead-Kirkhorn & Banasik, 2014, p. 568). JH’s signs and symptoms are not consistent with uremia. Uremia usually includes symptoms of accumulation of toxic metabolites causing additional symptoms such as pruritus, pericarditis, colitis, or bleeding (Copstead-Kirkhorn & Banasik, 2014, pp.

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