Asparagus Racemosus Case Study

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Acute oral toxicity study of the ethanolic root extracts revealed that different doses of Asparagus racemosus were non-toxic during the experimental period. Different doses of Asparagus racemosus root extracts received in the groups were showed the lethality to be zero. Among the all chronic diseases, diabetes mellitus is the most trivial and affiliated with hyperlipidemia and co-morbidities such as obesity, hypertension [66-68]. Hyperlipidemia is marked as a serious kind of intricacy for both clinical and experimental diabetes due to the subsequent metabolic complication [69]. Severe hyperglycemia is the most prominent reason of the entanglement of DM. Chronic entanglements are characterized by the dysfunction of various organs, especially the eyes (retinopathy), kidneys (nephropathy), nerves (neuropathy), heart (cardiomyopathy) and blood vessels [70,71].…show more content…
A potent Diabetogen named Alloxan is reduced to dialuric acid which is auto oxidized back to alloxan afterwards resulting in the production of H2O2, O2, O2- and hydroxyl radicals and genesis damages to the beta-cells of islets of langerhans [72]. Meanwhile, there is a humongous dwindling in insulin level and consequent increase in fasting blood glucose level [73].It consequences poor glycemic control and excessive catabolism of protein to provide amino acids for gluconeogenesis during insulin deficiency causing is polyuria, polyphagia and body weight reduction
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