'loneliness' to other words such as darkness, an inescapable reality or a prison cell. Of Mice and Men is a novel which explores the theme of loneliness and how it affects the characters—in either an unambiguous or abstract way. The story is set during the 1930s during the Great Depression in a place called Soledad. The name itself translates to 'loneliness' in Spanish. In John Steinbeck's novel, Of Mice and Men, he proves that loneliness