Abstract The Greek-Roman Isis temple is located on the west bank of Luxor; Upper Egypt was made of sandstone and decorated with different kinds of wall paintings. It suffers from many causes of deterioration and degradation mainly ground water, salt weathering, and different types of dirt accumulations on the relives and paint surface such as soot, grease, wax, biodeteriorated colored patches, bat patches, waste of birds and even house fly specks. All these lead to the gradual disappearance of paintings