Warfarin Vs Rivaroxaban

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TABLE 1:- Comparing And Contrasting Warfarin Vs. Rivaroxaban Recommendation Efficacy Safety Convenience Cost Warfarin • Effective • Slow onset • Narrow therapeutic range • Numerous food and drug interactions • Increases major and minor bleeding risks • Frequent physician visits and more frequent lifelong blood monitoring (INR) • Lower drug acquisition cost • Higher drug monitoring cost Rivaroxaban • Similar efficacy to warfarin • Reduced intracranial haemorrhage and fatal bleeding, however higher GI bleeding • Long-term safety data lacking • Once-daily dosing(20mg/d) • Renal dose adjustment: 15mg once daily • Less frequent physician visits • Higher drug acquisition cost • Lower drug monitoring cost Table 2: Advantages and Disadvantages

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