The Black Death, one of the most devastating pandemics in human history, is a watershed in the history of Europe, and it is also an important turning point in world trade. Before and after the Black Death, great changes have taken place in world trade, including the changes of trade volume, varieties of trade goods and trade routes. In addition, we know that the trade between Europe and Asia, whose development is the essential part of globalization, is always the most important part of the international